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2015 Meeting of the North Carolina Branch of the American Society for Microbiology

Saturday, 3 October 2015 at North Carolina State University, Raleigh, NC

IMPORTANT NOTE : The hurricane forecast is improving, it looks very unlikely that we will be significantly affected by Joquin.We're having a fair bit of rain unrelated to this hurricane, and have more in the forecast, but the meeting is proceeding rain or shine. Be safe on the roads!.


Sponsors (so far) :

When :

Saturday, October 3rd, 2015

Approximately 8:00AM - 5:00PM, with reception to follow.

Where :

David Clark Labs, NC State University, Raleigh, NC

> NCSU campus map

> Directions to David Clark Labs

> Directions to the Dan Allen parking deck

Parking :

Parking in the Dan Allen parking deck across the street (to the West) from the meeting venue is free to all after 5 pm during the week and on Saturdays and Sundays.

Acommodations :

For those of you who will be traveling the day before the meeting, or staying the night afterwards, there are many hotels in the general area; however, our block rooms for the meetings are now expired. Many hotels in the downlown/campus area are full, so look for hotels in the Cary/RTP area or Garner.

Registration and abstract submission :

The deadline for advance registration and abstract submssion has passed. You will still be able to register at the door.

Payment :

The meeting registration and branch memerbship fee is $20. If you joined or renewed your NC Branch membership for 2015 via the ASM eStore (NOT the same as your national ASM membership) this year, then the membership portion of this fee ($10) is already paid. Registrants will receive a program (including abstracts and attendee roster), a box lunch, morning and afternoon refreshments, and the reception.

The Registration and membership fee is payable at the door, or you can save time at registration by paying in advance with PayPal or credit card (using PayPal).

Meeting registration & NC ASM branch membership - $20 : Meeting registration ONLY (verify on the registration list to make sure you're already a branch member) - $10 : Vendor registration and
display table fee - $200 :
Other payments - $variable :

Please note that you can pay at any time up to the meeting, and at the door.

IF YOU NEED TO PAY AT THE MEETING, PLEASE PLAN TO BRING CASH. We will be able to handle creditcard or PayPal payments, but only one at a time, and not quickly.

Information for presenters :

Short talks

We are scheduling 15 minutes for each talk. This includes Q&A and switching time, so plan on about 12 minutes for your talk, a couple of minutes for Q&A, leaving us 1 minute for switching to the next speaker. Plan on bringing your presentation on a USB memory stick.


Posters will be mounted using small paper clamps onto 36" x 48" hardboard sheets, which can be placed onto the easels either horizontally (landscape) or vertically (portrait). We will provide clamps, boards, and easels; all you need to bring is your poster. If your poster is in panels or pieces, you should contact the meeting organizers ASAP.

Schedule :



Poster and talk set-up
Breakfast/Coffee break
Award Committees meeting/organization
Vendors/Sponsors set-up


Wrennie Edwards

Introductory comments

Session 1 : Wrennie Edwards, Chair


Casey Theroit

Secondary bile acids shape colonization resistance against Clostridium difficile in the large intestine 


Michael Taveirne

A new Function for a Classic Regulator: The Zinc and Oxidative Stress Regulator (ZOR) in Vibrio cholerae.


Brittany Miller

A novel component of the specialized SecA2 protein export pathway in Mycobacterium tuberculosis


Cynthia Darnell

Systematic deletion analysis of transcription factors and their responses to environmental stress in the halophilic archaeon Halobacterium salinarum


Sarah Stanley

Preventing Nosocomial Infections: Antimicrobial Photodynamic Textiles


Poster session 1 (Even-numbered poster should be attended)
Coffee break Sponsored by Alpha Aesar

Session 2 : James Brown, Chair


Stephanie Mathews

Degradation of Lignin and Lignin-Related Compounds by Paenibacillus glucanolyticus


Erin Almand

Binding of Human Norovirus to Fecally Isolated Bacteria


Marc Muraski

Cloning and characterization of tRNA(Ile) Lysidine Synthetase from Burkholderia cenocepacia


Mara Cashay

Response of bacterial Mn(II)-oxidizing consortia to exogenous carbon sources in caves in the southern Appalachian Mountains 


Poster Session 2 (unattended)

Session 3 : Art Frampton, Chair


Carolina Caro-Vegas

The novel drug MLN0128, a dual mTORC1/2 inhibitor suppresses proliferation of primary effusion lymphoma cell lines


Bryan Troxell

It's Getting Hot in Here: Temperature-dependent Gene Regulation in Salmonella


Sarah Cauley

Survival of Probiotic Lactobacillus plantarum and Pediococcus acidilactici in Refrigerated, Acidified Cucumbers


Melanie Lee-Brown



Poster session 3 (Odd-numbered poster should be attended)
Coffee break

Plenary session : Wrennie Edwards and Ece Karatan, Chairs


Heidi Trusheim
NC Invitational Lecture

NVS Influenza Vaccines


Coffee break
Awards committee meetings


Briana Burton
ASM Branch Lecture

Rules of the Road: Motor Proteins that Mediate Chromosome Segregation



Wrennie Edwards

Concluding remarks


Jim Brown

Business meeting
Officer election





ASM Branch Lecture

Briana Burton
Harvard University

Rules of the Road: Motor Proteins that Mediate Chromosome Segregation

Dr. Briana Burton is Associate Professor in Molecular and Cellular Biology at Harvard University. The research in her laboratory has provided several key advances in understanding biochemical mechanisms underlying the physically challenging problem of macromolecule transport at membrane barriers. Her group combines state-of-the-art biochemistry and imaging approaches with classical microbiological techniques to explore the action of membrane-associated DNA transporters involved in DNA uptake and chromosome segregation and in protein secretion.

NC Invited Lecture

Heidi Trusheim
NVS Influenza Vaccines

Product Steward for Flu Cell Culture

Currently, the majority of the influenza vaccines distributed globally derive from manufacture processes first developed in the 1940s and 1950s and is based on a technology which relies on replicating the influenza viruses in embryonated hens’ eggs. This production platform depends on a continuous supply of eggs which can become problematic in case of a pandemic outbreak because of a sudden reduction in egg supply. It has also shown that human influenza viruses isolated and grown in eggs can acquire amino acid changes in the hemagglutinin protein, the antigen in the vaccine, which alters the immunogenic property of this important protein. More recently, cell culture based technology became available as a method for the production of influenza vaccines in addition to eggs, which presents a number of benefits and also enables a more rapid response to the increasing worldwide demand of influenza vaccines.  In 2012 Novartis licensed Flucelvax™, a trivalent vaccine manufactured on a platform utilizing the canine derived continuous cell line MDCK33016PF to propagate the influenza virus, for distribution in the US. The presentation reviews the cell culture based process developed by Novartis for the manufacture of seasonal and pandemic influenza vaccines. The talk also provides an insight into a collaboration with the World Health Organization to support the effort to overcome challenges in the provision of reference viruses used in the initiation of the influenza vaccine production.

Elections :

The meeting will be concluded by a brief business meeting, including the election of new officers.

If you would like to nominate someone or volunteer to run for office, please feel free to do so by email to Jim Brown.

Presentation Awards :

Web Links :

Organizing Committee :

Wrennie Edwards (President-elect)
Ece Karatan (President)
James W. Brown (Secretary)
Ece Karatan (Councilor)

Contact :

Wrennie Edwards
QC Analyst III Virology/PCR
NVS Influenza Vaccines
Holly Springs, NC

Last updated by James W. Brown | Department of Biological Sciences | College of Sciences | NC State University